The 2021 Annual meeting was held virtually on the 24th and 25th March 2021. We were delighted to welcome Professor Michael Murphy who presented the John Farndon Lecture and Dr. Muriel Brackstone who presented the BJS Lecture. Over the course of the two days we heard presentations from the Australia, Ireland, UK and USA. We were delighted to welcome the Prize Winners from the Society of University Surgeons (SUS) in America – Hallie J. Quiroz and the European Society for Surgical Research (ESSR) – Can Gollmann-Tepekoylu.
Congratulations to Emily Thompson winner of the 2021 Patey Prize. Below is a full list of all the winners from the March meeting.
|Patey Prize Winner:|
|EX VIVO NORMOTHERMIC MACHINE PERFUSION FACILITATES GYMNOTIC DELIVERY OF RNA INTERFERENCE THERAPEUTICS IN DONOR KIDNEYS|
|ER Thompson (1,2,3), A Sewpaul(1,2,3), R Figuereido(1,2,3), L Bates(1,3), JR Ferdinand (3,4), Connelly CM (1), Hosgood SA (3, 4), Nicholson, ML (3, 4), Clatworthy MR (3, 4), Ali S (1, 3), Wilson CH (1, 2, 3), Sheerin NS (1, 2, 3)|
|1) Translational and Clinical Research Institute, Newcastle University, 2) Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, 3 NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, 4 Department of Surgery, University of Cambridge|
|Norman Williams Prize|
|EVALUATION OF RISK PREDICTION MODELS FOR POSTOPERATIVE PULMONARY COMPLICATIONS IN ADULTS UNDERGOING MAJOR ABDOMINAL SURGERY: A SYSTEMATIC REVIEW AND EXTERNAL VALIDATION STUDY IN THE RESPIRATORY COMPLICATIONS AFTER ABDOMINAL SURGERY (RECON) COHORT|
|Murray V. Student Audit and Research in Surgery (STARSurg) Collaborative|
|Academic Department of Surgery, Room 29, 4th Floor, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Edgbaston, Birmingham|
|Kevin Burnand Prize|
|INTERTUMOURAL HETEROGENEITY IN THE STRUCTURE OF THE NEUROVASCULAR UNIT IN GLIOMA: A RETROSPECTIVE OBSERVATIONAL COHORT STUDY|
|S Keni, C Smith, G Thompson, PM Brennan|
|The University of Edinburgh|
|Medical Student Prize|
|THE EFFECT OF MALNUTRITION ON EARLY OUTCOMES AFTER CANCER SURGERY: AN INTERNATIONAL PROSPECTIVE COHORT STUDY|
|Aya M Riad, Stephen R Knight, Ewen M Harrison on behalf of GlobalSurg Collaborative|
|University of Edinburgh|
|RCS(Eng) Research Fellows Symposium Prize|
|ACID CERAMIDASE: A POTENTIAL BIOMARKER FOR LOCALLY ADVANCED RECTAL CANCER|
|Rachael Elizabeth Clifford1, Naren Govindarajah1, David Bowden1, Paul Sutton1, Jason Parsons1, Dale Vimalachandran2|
|(1) The Institute of Translational Medicine, The University of Liverpool, (2) The Countess of Chester Hospital|
Wednesday 24th March 2021
- 16.00 – John Farndon Lecture: Professor Michael Murphy
- 16.30 – RCS(Eng) Fellows Symposium
- 18.00 – Cohort Studies Presentations
- 18.00 – Basic Sciences Presentations
- 19.00 – Patey Prize Session
Thursday 25th March 2021
- 16.00 – COVID Presentations
- 17.00 – Systematic Review/Meta Analysis Presentations
- 17.00 – Education and Training Presentations
- 17.45 – Experimental & Database Presentations
- 17.45 – ASiT Innovations in Training Session
- 18.45 – Patey Prize Session
- 19.45 – BJS Lecture: Dr. Muriel Brackstone
- 20.15 – Presentation of Prizes
Dr. Brackstone Bio
She obtained her Medical Degree and General Surgical Residency at the University of Western Ontario and her fellowship in Breast Surgical Oncology at the University of Toronto. As a practicing surgeon, she obtained her Masters Degree in Epidemiology & Biostatistics followed by a PhD in Clinical Trials (Dept Pathology).
She is the Medical Director of London’s Breast Care Program and founding Director of the London Tumour Biobank, which is a biospecimen repository and translational research platform for serial imaging, tumour biopsies and blood collection with life-long clinical follow-up data. She is the lead author of national guidelines for the management of locally advanced breast cancer and management of the axilla. She co-founded Canada’s only hands-on Oncoplastic Surgery Training Program and has developed the standards for the role of oncoplastic surgery in breast conservation in Canada.
She has conducted a number of clinical trials most notably in the neoadjuvant setting, including the role of concurrent neoadjuvant radiation with chemotherapy in breast cancer, the role of probiotics on the inflammation-inducing breast microbiome, hypofractionated radiation in the neoadjuvant setting and its role in immune priming, with an ongoing research program in prone hypofractionated radiation concurrent with immune checkpoint inhibitors. She has over 100 peer reviewed publications with 50 peer reviewed grants to date. Dr. Brackstone is also a practicing general surgeon with four young children.
Professor Mike Murphy Bio
Mike Murphy received his BA in chemistry at Trinity College, Dublin in 1984 and his PhD in Biochemistry at Cambridge University in 1987. After stints in the USA, Zimbabwe, and Ireland he took up a faculty position in the Biochemistry Department at the University of Otago, Dunedin, New Zealand in 1992. In 2001 he moved to the MRC Mitochondrial Biology Unit in Cambridge, UK (then called the MRC Dunn Human Nutrition Unit) where he is a programme leader.
Murphy’s research focuses on the roles of reactive oxygen species in mitochondrial function and pathology. In particular he has pioneered the targeting of bioactive and probe molecules to mitochondria in vivo. This general methodology is now widely used. Prominent mitochondria-targeted compounds are antioxidants, such as MitoQ, which protects against oxidative damage in ischaemia-reperfusion injury. Murphy and Rob Smith developed MitoQ as an oral drug which has been used in two Phase II trials so far. This work established mitochondria as a relevant drug target and opened up the field of mitochondrial pharmacology. The Murphy group has gone on to create MitoSNO, a mitochondria-targeted nitric oxide donor which is now being developed as a potential therapy for cardiac ischaemia-reperfusion injury, and MitoG to treat diabetes.
Recently his work has extended to determining the mechanism by which mitochondria produce free radicals during ischaemia-reperfusion injury in heart attack and stroke. Murphy is Professor of Mitochondrial Redox Biology at the University of Cambridge, a Wellcome Trust Investigator, honorary research Professor at the University of Otago, New Zealand, a recipient of the Keilin Medal from the Biochemical Society, an honorary Fellow of the Royal Society of New Zealand and a Fellow of the Academy of Medical Sciences (FMedSci). He has published more than 345 peer reviewed papers, which have garnered more than 39,000 citations and he has an h-index of 106.